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2-Fluorobenzonitrile CAS NO 394-47-8


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CAS No.:394-47-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluorobenzonitrile is a versatile fluorinated aromatic nitrile compound, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the cyano group, enabling precise molecular construction. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including kinase inhibitors and CNS-targeting drugs.
  • Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
  • Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic display and lighting technologies.
  • Functional Polymer Monomer: Incorporates into polymers to impart specific chemical resistance, thermal stability, or optical properties.
  • Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution.
  • Fluorine Chemistry Research: A standard substrate for studying the effects of fluorine substitution on aromatic systems and reaction pathways.

Basic Information

Product Name 2-Fluorobenzonitrile
CAS No. 394-47-8
Molecular Formula C7H4FN
Molecular Weight 121.11 g/mol
Synonyms o-Fluorobenzonitrile; 2-Fluorobenzene carbonitrile; 2-Cyanofluorobenzene; Benzonitrile, 2-fluoro-; o-Cyanofluorobenzene; 1-Fluoro-2-cyanobenzene; 2-Fluorophenyl cyanide; Fluorobenzonitrile (unspecified isomer)
EINECS 206-903-1

Quality Control

Our 2-Fluorobenzonitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 98.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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