Description

5-Fluoro-2-Nitrobenzotrifluoride is a versatile fluorinated aromatic building block of significant commercial importance. Its unique structure, featuring both a nitro group and a trifluoromethyl group on a fluorinated benzene ring, makes it a critical intermediate in advanced organic synthesis. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex, high-performance dyes and pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki and Buchwald-Hartwig couplings, enabling complex molecule assembly.
• Fluorine Chemistry Studies: A valuable reagent for academic and industrial research exploring the effects of fluorination on molecular properties.

Basic Information

Product Name	5-Fluoro-2-Nitrobenzotrifluoride
CAS No.	393-86-2
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	2-Nitro-5-fluorobenzotrifluoride; 1-Fluoro-4-nitro-2-(trifluoromethyl)benzene; 5-Fluoro-2-nitro-α,α,α-trifluorotoluene; 2-Nitro-α,α,α,5-tetrafluorotoluene; Benzene, 1-fluoro-4-nitro-2-(trifluoromethyl)-; 5-Fluoro-2-nitrobenzylidene trifluoride; 393-86-2; 5-Fluoro-2-nitro-α,α,α-trifluoromethylbenzene
EINECS	206-896-8

Quality Control

Every batch of 5-Fluoro-2-Nitrobenzotrifluoride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.