Description

4'-Nitro-3'-(trifluoromethyl)acetanilide is a specialized aromatic intermediate featuring a nitro group and a trifluoromethyl substituent on the aniline ring. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of target molecules for drug discovery programs, especially those requiring the trifluoromethyl pharmacophore.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and fungicides, where the nitro and CF3 groups contribute to biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for the construction of complex heterocycles and functionalized anilines.
• Material Science Research: Acts as a monomer or modifying agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	4'-Nitro-3'-(trifluoromethyl)acetanilide
CAS No.	393-12-4
Molecular Formula	C9H7F3N2O3
Molecular Weight	248.16 g/mol
Synonyms	N-(4-Nitro-3-(trifluoromethyl)phenyl)acetamide; 2',4'-Dinitro-5'-(trifluoromethyl)acetanilide; 1-(4-Nitro-3-(trifluoromethyl)phenyl)ethan-1-one; Acetamide, N-[4-nitro-3-(trifluoromethyl)phenyl]-; 4-Nitro-3-trifluoromethylacetanilide; 3-Trifluoromethyl-4-nitroacetanilide; 393-12-4
EINECS	Contact for details

Quality Control

Our 4'-Nitro-3'-(trifluoromethyl)acetanilide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.