Description

4-Iodo-1-Nitro-2-(Trifluoromethyl)Benzene is a high-purity, multi-functional halogenated aromatic building block of significant commercial and research interest. Its unique structure, featuring iodine, nitro, and trifluoromethyl substituents, makes it a versatile intermediate for synthesizing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by pharmaceutical, agrochemical, and advanced materials research sectors for applications in drug discovery, ligand synthesis, and the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic cores or trifluoromethyl groups to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the iodine atom provides a handle for further functionalization via cross-coupling reactions.
• Material Science Research: Acts as a building block for creating organic electronic materials, liquid crystals, and polymers, leveraging the electron-withdrawing nature of the nitro and trifluoromethyl groups.
• Ligand and Catalyst Development: Employed in organometallic chemistry to synthesize sophisticated ligands for catalysis, where the iodine substituent is pivotal for metal complexation.
• Chemical Research & Development: A valuable reagent for exploring new organic transformations, such as Suzuki, Stille, and Sonogashira cross-coupling reactions, due to the reactivity of the aryl-iodide bond.
• Dye and Pigment Intermediate: Can be used in the synthesis of specialized dyes and pigments where the introduction of halogen and nitro groups alters color properties and lightfastness.

Basic Information

Product Name	4-Iodo-1-Nitro-2-(Trifluoromethyl)Benzene
CAS No.	393-10-2
Molecular Formula	C7H3F3INO2
Molecular Weight	316.99 g/mol
Synonyms	1-Iodo-4-nitro-2-(trifluoromethyl)benzene; 2-Trifluoromethyl-4-iodonitrobenzene; 4-Iodo-2-(trifluoromethyl)nitrobenzene; 4-Iodo-1-nitro-α,α,α-trifluoro-o-xylene; 2-(Trifluoromethyl)-4-iodonitrobenzene; Benzene, 4-iodo-1-nitro-2-(trifluoromethyl)-; NSC 404083
EINECS	Contact for details

Quality Control

Our 4-Iodo-1-Nitro-2-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers. Recommended storage temperature is between 15°C and 25°C. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.