Description

n-(2-Nitro-3-(Trifluoromethyl)Phenyl)Acetamide is a specialized aromatic acetamide derivative featuring both nitro and trifluoromethyl functional groups, which are critical for imparting unique reactivity and physicochemical properties. This compound serves as a valuable advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro and trifluoromethyl motifs.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex azo dyes and high-performance pigments.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold in drug discovery.

Basic Information

Product Name	n-(2-Nitro-3-(Trifluoromethyl)Phenyl)Acetamide
CAS No.	387-19-9
Molecular Formula	C9H7F3N2O3
Molecular Weight	248.16 g/mol
Synonyms	N-[2-Nitro-3-(trifluoromethyl)phenyl]acetamide; 2'-Nitro-3'-(trifluoromethyl)acetanilide; Acetamide, N-[2-nitro-3-(trifluoromethyl)phenyl]-; 2-Nitro-α,α,α-trifluoro-m-acetotoluidide; 387-19-9; NSC 406106; N-(2-Nitro-3-trifluoromethylphenyl)acetamide
EINECS	Contact for details

Quality Control

Our n-(2-Nitro-3-(Trifluoromethyl)Phenyl)Acetamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The compound should be considered moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.