Description

2-Nitrobenzotrifluoride is a specialized aromatic nitro compound containing a trifluoromethyl group, valued for its role as a versatile chemical intermediate. Its unique structure makes it a critical building block for synthesizing more complex molecules, particularly in advanced material and pharmaceutical research. This compound is essential for manufacturers and R&D laboratories in the agrochemical, pharmaceutical, and specialty chemical sectors seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the nitro and trifluoromethyl groups contribute to biological activity.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating specialized azo dyes and organic pigments with specific color fastness and chemical resistance properties.
• Liquid Crystal & Electronic Material Research: Employed in the development of fluorinated components for liquid crystal displays (LCDs) and other electronic materials.
• Organic Synthesis & Cross-Coupling Reactions: Acts as a substrate in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl structures.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new synthetic pathways and creating novel fluorinated compounds.

Basic Information

Product Name	2-Nitrobenzotrifluoride
CAS No.	384-22-5
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	1-Nitro-2-(trifluoromethyl)benzene; α,α,α-Trifluoro-o-nitrotoluene; 2-(Trifluoromethyl)nitrobenzene; o-Nitrobenzotrifluoride; o-Nitro-α,α,α-trifluorotoluene; 2-Nitro-α,α,α-trifluorotoluene; Benzene, 1-nitro-2-(trifluoromethyl)-; o-Trifluoromethylnitrobenzene
EINECS	206-847-5

Quality Control

Our 2-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Yellow to light brown liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%
Density (at 20°C)	~1.40 g/cm³
Refractive Index (n20D)	~1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.