Description

(6A, 11)-9-Fluoro-11,17,21-Trihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione is a high-purity synthetic steroid derivative of significant pharmaceutical interest. This compound matters as a key intermediate in the research and development of potent corticosteroid medications, offering a critical building block for advanced therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on steroid chemistry and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of advanced corticosteroid drugs.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical manufacturing.
• Process Chemistry: Employed in scaling up and optimizing synthetic routes for fluorinated steroid production.
• Biochemical Research: Utilized in studies investigating the mechanisms of glucocorticoid and anti-inflammatory actions.

Basic Information

Product Name	(6A, 11)-9-Fluoro-11,17,21-Trihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione
CAS No.	382-52-5
Molecular Formula	C₂₂H₂₉FO₅
Molecular Weight	392.46 g/mol
Synonyms	9α-Fluoro-11β,17α,21-Trihydroxy-6α-Methylpregna-1,4-Diene-3,20-Dione; 6α-Methyl-9α-fluoroprednisolone; 9α-Fluoro-6α-methylprednisolone; 6α-Methyl-9α-fluoro-δ¹-hydrocortisone; 6α-Methyl-9α-fluoroprednisolone; Fluprednisolone Intermediate; 6α-Methyl-9α-fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our (6A, 11)-9-Fluoro-11,17,21-Trihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.