Description

2-Fluoroethanimidamide Hydrochloride Hemihydrate is a high-purity fluorinated amidine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive fluorine-containing building block for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated heterocycles and active pharmaceutical ingredients (APIs), leveraging the fluorine atom to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the fluorinated amidine moiety can enhance biological activity and environmental profile.
• Chemical Biology & Proteomics: Acts as a reagent for protein labeling and bioconjugation strategies, exploiting the reactive amidine group for selective modification.
• Material Science: Serves as a precursor for fluorinated polymers, coatings, and electronic materials that require specific dielectric or surface properties.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed and other metal-mediated coupling reactions to introduce fluorinated functional groups into complex scaffolds.

Basic Information

Item	Detail
Product Name	2-Fluoroethanimidamide Hydrochloride Hemihydrate
CAS No.	381-63-5
Molecular Formula	C₂H₆ClFN₂O·0.2H₂O
Molecular Weight	Contact for details
Synonyms	2-Fluoroacetamidine Hydrochloride Hemihydrate; 2-Fluoroethanimidamide Monohydrochloride Hemihydrate; Acetamidine, 2-fluoro-, hydrochloride, hemihydrate; 2-Fluoroacetamidine HCl Hemihydrate; 1-Amino-2-fluoroethaniminium Chloride Hemihydrate; Guanidine, (2-fluoroethyl)-, hydrochloride, hemihydrate; (2-Fluoroethyl)guanidine Hydrochloride Hemihydrate
EINECS	Contact for details

Quality Control

Our 2-Fluoroethanimidamide Hydrochloride Hemihydrate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.