Description

5-Fluoro-1-Pentanesulfonyl Fluoride is a specialized organofluorine building block featuring a reactive sulfonyl fluoride group. This compound is valued for its role in the synthesis of sulfonamide derivatives and as a key intermediate in the development of pharmaceuticals and agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the life sciences sector for applications in medicinal chemistry, chemical biology, and material science.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly sulfonamide-based therapeutics.
• Chemical Biology Probe Development: Used in activity-based protein profiling (ABPP) and covalent inhibitor design due to the reactivity of the sulfonyl fluoride moiety.
• Agrochemical Synthesis: Serves as an intermediate in the production of advanced pesticides and herbicides.
• Material Science Research: Employed in the creation of functionalized polymers and advanced materials with specific surface properties.
• Fluorination Reagent: Acts as a source of fluorine atoms in organic synthesis for introducing fluorinated functional groups.

Basic Information

Item	Detail
Product Name	5-Fluoro-1-Pentanesulfonyl Fluoride
CAS No.	372-99-6
Molecular Formula	C5H10F2O2S
Molecular Weight	172.20 g/mol
Synonyms	5-Fluoropentanesulfonyl Fluoride; 1-Fluoro-5-pentanesulfonyl Fluoride; 5-Fluoropentane-1-sulfonyl Fluoride; ω-Fluoropentanesulfonyl Fluoride; Pentanesulfonyl Fluoride, 5-fluoro-; 372-99-6; 5-Fluoroamylsulfonyl Fluoride
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-Pentanesulfonyl Fluoride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. All products undergo comprehensive analytical testing, including HPLC, NMR, and GC analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.