Description

3,4-Difluoronitrobenzene is a high-purity fluorinated aromatic intermediate essential for advanced organic synthesis. Its unique structure, featuring both nitro and fluorine substituents, makes it a versatile building block for creating complex molecules with tailored properties. This compound is particularly valuable for R&D and production in the pharmaceutical and agrochemical sectors, where it serves as a precursor for active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated benzene core.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated compounds used in electronic displays and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated to introduce fluorine functionality into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and pigments where fluorination alters color fastness and solubility.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.
• Nucleophilic Aromatic Substitution: The nitro and fluorine groups are reactive sites for substitution, enabling the introduction of various amines, alkoxides, and other nucleophiles.
• Research & Development: A valuable tool for medicinal chemistry and material science research exploring structure-activity relationships.

Basic Information

Product Name	3,4-Difluoronitrobenzene
CAS No.	369-34-6
Molecular Formula	C6H3F2NO2
Molecular Weight	159.09 g/mol
Synonyms	1,2-Difluoro-4-nitrobenzene; 4-Nitro-1,2-difluorobenzene; 3,4-Difluoro-1-nitrobenzene; Benzene, 1,2-difluoro-4-nitro-; NSC 404071; 3,4-DFNB
EINECS	206-719-9

Quality Control

Our 3,4-Difluoronitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global customer base. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.