Description

3-(Trifluoromethyl)Benzonitrile is a versatile fluorinated aromatic nitrile building block essential for advanced organic synthesis. Its value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the reactive cyano functionality, enabling precise molecular modifications. This high-purity intermediate is critically needed by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a precursor for heterocyclic compounds like benzimidazoles and triazoles.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized fluorinated dyes and pigments.

Basic Information

Product Name	3-(Trifluoromethyl)Benzonitrile
CAS No.	368-77-4
Molecular Formula	C8H4F3N
Molecular Weight	171.12 g/mol
Synonyms	m-(Trifluoromethyl)benzonitrile; 3-Cyanobenzotrifluoride; α,α,α-Trifluoro-m-tolunitrile; m-Trifluoromethylbenzonitrile; 3-Trifluoromethylphenyl cyanide; Benzonitrile, 3-(trifluoromethyl)-; 3-Trifluoromethyl benzonitrile; m-Cyanobenzotrifluoride
EINECS	206-718-4

Quality Control

Our 3-(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.