Description

2-Fluoro-5-Iodonitrobenzene is a versatile halogenated nitrobenzene derivative that serves as a critical building block in advanced organic synthesis. Its unique combination of fluorine, iodine, and nitro functional groups makes it a valuable precursor for constructing complex molecular architectures. This high-purity intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine and iodine substituents modulate biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to form biaryl structures.
• Nucleophilic Aromatic Substitution: The fluorine atom activated by the nitro group is a prime site for substitution with various nucleophiles.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization and route scouting.

Basic Information

Product Name	2-Fluoro-5-Iodonitrobenzene
CAS No.	364-75-0
Molecular Formula	C6H3FINO2
Molecular Weight	267.00 g/mol
Synonyms	1-Fluoro-2-nitro-4-iodobenzene; 2-Fluoro-1-nitro-4-iodobenzene; 4-Iodo-2-fluoronitrobenzene; 2-Fluoro-4-iodonitrobenzene; 2-Fluoro-5-iodo-1-nitrobenzene; 5-Iodo-2-fluoronitrobenzene; Benzene, 2-fluoro-5-iodo-1-nitro-; 2-Fluoro-5-iodonitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodonitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.