Description

4-Methylsulfonyl-3-Nitrobenzotrifluoride is a high-value, multi-functional aromatic intermediate featuring both a nitro and a methylsulfonyl group on a trifluoromethylated benzene ring. This unique structure makes it a critical building block for synthesizing complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bioactive molecules, including potential kinase inhibitors and other targeted therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the nitro and sulfone functionalities.
• Material Science Research: Serves as a monomer or functionalizing agent for creating specialty polymers and advanced organic electronic materials.
• Dye and Pigment Intermediate: Employed in the production of specialized colorants and photographic chemicals.
• Cross-Coupling Reactions: The nitro and sulfonyl groups can be transformed or displaced, making it a versatile substrate for Suzuki, Buchwald-Hartwig, and other metal-catalyzed couplings.

Basic Information

Product Name	4-Methylsulfonyl-3-Nitrobenzotrifluoride
CAS No.	364-48-7
Molecular Formula	C8H6F3NO4S
Molecular Weight	269.20 g/mol
Synonyms	3-Nitro-4-(methylsulfonyl)benzotrifluoride; 4-(Methylsulfonyl)-3-nitrobenzotrifluoride; 1-Methylsulfonyl-2-nitro-4-(trifluoromethyl)benzene; Benzene, 1-(methylsulfonyl)-2-nitro-4-(trifluoromethyl)-; α,α,α-Trifluoro-4-methylsulfonyl-3-nitro-toluene
EINECS	Contact for details

Quality Control

Every batch of 4-Methylsulfonyl-3-Nitrobenzotrifluoride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A detailed Certificate of Analysis (COA) documenting purity, identity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.