Description

1-(Ethylsulfonyl)-2-Nitro-4-(Trifluoromethyl)Benzene is a high-purity, specialized organic intermediate featuring a unique combination of sulfonyl, nitro, and trifluoromethyl functional groups. This compound is valued for its role as a critical building block in advanced synthetic chemistry, enabling the development of complex molecules with tailored properties. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethyl moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the nitro and sulfonyl groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and organic pigments.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct biaryl systems.
• Organic Synthesis Building Block: Provides a versatile scaffold for further functionalization in medicinal chemistry and chemical biology research programs.

Basic Information

Product Name	1-(Ethylsulfonyl)-2-Nitro-4-(Trifluoromethyl)Benzene
CAS No.	364-00-1
Molecular Formula	C9H8F3NO4S
Molecular Weight	283.22 g/mol
Synonyms	2-Nitro-α,α,α-trifluoro-p-(ethylsulfonyl)toluene; 1-Ethylsulfonyl-2-nitro-4-trifluoromethylbenzene; 4-(Ethylsulfonyl)-3-nitrobenzotrifluoride; Benzene, 1-(ethylsulfonyl)-2-nitro-4-(trifluoromethyl)-; NSC 406106; Ethyl 2-nitro-4-(trifluoromethyl)phenyl sulfone
EINECS	Contact for details

Quality Control

Our 1-(Ethylsulfonyl)-2-Nitro-4-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.