Description

1,3,3,4,4-Pentafluoro-2-Methoxycyclobutene is a specialized fluorinated organic compound that serves as a high-value building block in advanced chemical synthesis. Its unique structure, featuring a cyclobutene ring with pentafluoro and methoxy substituents, makes it a critical intermediate for developing novel materials with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and advanced materials sectors for creating new active ingredients and functional polymers. Its controlled reactivity and fluorine content are key to enhancing product performance and stability in demanding applications.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Advanced Material Precursor: Serves as a key monomer or building block for the development of specialty polymers, coatings, and resins with enhanced chemical resistance, thermal stability, and low surface energy.
• Agrochemical Research: Employed in creating new generations of herbicides, fungicides, and pesticides where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Liquid Crystal & Electronic Chemicals: Acts as a synthetic intermediate for fluorinated liquid crystals and dielectric fluids used in display technologies and specialized electronics.
• Organic Synthesis & Catalysis: Utilized in academic and industrial research as a versatile reagent for constructing complex, fluorinated molecular architectures and exploring new catalytic cycles.

Basic Information

Product Name	1,3,3,4,4-Pentafluoro-2-Methoxycyclobutene
CAS No.	359-98-8
Molecular Formula	C5H3F5O
Molecular Weight	174.07 g/mol
Synonyms	2-Methoxy-1,3,3,4,4-pentafluorocyclobut-1-ene; Pentafluoromethoxycyclobutene; 1,3,3,4,4-Pentafluoro-2-methoxy-1-cyclobutene; 2-Methoxy-1,3,3,4,4-pentafluorocyclobutene; 359-98-8; Methoxy-pentafluorocyclobutene
EINECS	Contact for details

Quality Control

Our 1,3,3,4,4-Pentafluoro-2-Methoxycyclobutene is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to verify identity and quantify purity and impurity profiles. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment. We support cGMP and ISO 9001 standards for our manufacturing processes, ensuring reliability for critical research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Recommended storage temperature is between 2°C and 8°C (refrigerated) to maintain optimal stability for extended periods. Keep away from heat, sparks, and open flames. The container must be kept tightly sealed in a dry environment to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.