Description

Fluocinonide is a potent synthetic corticosteroid widely recognized for its anti-inflammatory and antipruritic properties. This high-purity active pharmaceutical ingredient (API) is essential for the formulation of effective topical dermatological treatments. It is primarily used by pharmaceutical manufacturers and research institutions developing solutions for inflammatory skin conditions.

Application

• Topical Corticosteroid Formulations: Primary API in creams, ointments, gels, and solutions for treating severe skin inflammation.
• Dermatological Therapeutics: Key ingredient in prescription medications for conditions such as psoriasis, eczema, atopic dermatitis, and contact dermatitis.
• Veterinary Medicine: Used in topical preparations for managing inflammatory skin disorders in animals.
• Clinical Research: Serves as a reference standard and active compound in pharmacological studies and new drug development.
• Compounding Pharmacy: Utilized by specialized pharmacies to prepare customized topical medication strengths for specific patient needs.

Basic Information

Item	Details
Product Name	Fluocinonide
CAS No.	356-12-7
Molecular Formula	C26H32F2O7
Molecular Weight	494.53 g/mol
Synonyms	6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; Fluocinonide; Lidex; Topsyn; Vasoderm; 6α,9α-Difluoroprednisolone 16,17-acetonide; Fluocinolone acetonide 21-acetate (common misnomer)
EINECS	206-614-9

Quality Control

Our Fluocinonide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity pharmaceutical standards, with specifications typically aligned with major pharmacopoeial guidelines. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.