Description

4-Fluoronitrobenzene is a versatile fluorinated aromatic intermediate essential for synthesizing complex organic molecules. Its unique combination of a nitro group and a fluorine atom on the benzene ring makes it a valuable building block for introducing fluorinated aniline derivatives into target compounds. This product is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated anilines, which are crucial scaffolds for active pharmaceutical ingredients (APIs), including various drugs and biologics.
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for creating fluorinated dyes and organic pigments with specific color fastness and properties.
• Liquid Crystal & OLED Materials: Employed in the research and development of fluorinated compounds for electronic displays and advanced optoelectronic devices.
• Polymer Modification: Acts as a monomer or modifier in the synthesis of specialty polymers and resins to impart specific chemical resistance or thermal properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl structures in fine chemical synthesis.

Basic Information

Product Name	4-Fluoronitrobenzene
CAS No.	350-46-9
Molecular Formula	C6H4FNO2
Molecular Weight	141.10 g/mol
Synonyms	1-Fluoro-4-nitrobenzene; p-Fluoronitrobenzene; 4-Nitrofluorobenzene; p-Nitrofluorobenzene; PNFB; 4-FNB; FNB
EINECS	206-499-1

Quality Control

Our 4-Fluoronitrobenzene is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong reducing agents and bases. The container should be kept upright and securely sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Pale yellow to yellow crystalline solid or liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Melting Point	21°C - 27°C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.