Description

2-Amino-5-Fluoro-3-Nitrobenzotrifluoride is a high-value fluorinated aromatic amine derivative, serving as a critical building block in advanced chemical synthesis. Its unique trifluoromethyl and nitro-substituted aniline structure makes it indispensable for creating complex molecules with tailored properties. This intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting central nervous system and oncological diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Dye and Pigment Manufacturing: Acts as a versatile intermediate for producing high-performance, light-fast fluorinated dyes and pigments.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions like Buchwald-Hartwig amination for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	2-Amino-5-Fluoro-3-Nitrobenzotrifluoride
CAS No.	344-29-6
Molecular Formula	C7H4F4N2O2
Molecular Weight	224.12 g/mol
Synonyms	2-Amino-5-fluoro-3-nitrobenzotrifluoride; 5-Fluoro-2-amino-3-nitrobenzotrifluoride; 2-Amino-α,α,α,5-tetrafluoro-3-nitrobenzotrifluoride; 3-Nitro-5-fluoro-2-aminobenzotrifluoride; 2-Amino-5-fluoro-3-nitro-α,α,α-trifluorotoluene; Benzenamine, 2-amino-5-fluoro-3-nitro-α,α,α-trifluoro-; 344-29-6; 2-Amino-5-fluoro-3-nitro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Fluoro-3-Nitrobenzotrifluoride is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing all critical parameters for your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.