Description

(8S,9R,10S,11S,13R,14S,17S)-17-Acetyl-9-Fluoro-11-Hydroxy-10,13-Dimethyl-2,6,7,8,11,12,14,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthren-3-One is a high-purity synthetic steroid derivative, a key intermediate in the research and development of novel pharmaceutical compounds. Its precise stereochemistry and functional groups make it a valuable building block for medicinal chemistry, particularly in the synthesis of fluorinated corticosteroids and other bioactive molecules. This compound is essential for pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on advanced steroid chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent fluorinated corticosteroid drugs and other steroidal active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents with anti-inflammatory or hormonal activity.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical manufacturing, ensuring batch-to-batch consistency.
• Biochemical Research: Employed in studies investigating steroid hormone receptor interactions and metabolic pathways.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value steroidal compounds.

Basic Information

Product Name	(8S,9R,10S,11S,13R,14S,17S)-17-Acetyl-9-Fluoro-11-Hydroxy-10,13-Dimethyl-2,6,7,8,11,12,14,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthren-3-One
CAS No.	339-02-6
Molecular Formula	C₂₁H₂₇FO₃
Molecular Weight	346.44 g/mol
Synonyms	9α-Fluoro-11β,17α,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17-Acetate; 9-Fluoro-11β,17,21-Trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-Acetate; Fluorinated Corticosteroid Intermediate; 9α-Fluoro-16α-methylprednisolone 17-acetate; 9-Fluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17-acetate; 339-02-6; 9-Fluoro-16α-methylprednisolone 17-acetate
EINECS	Contact for details

Quality Control

Our (8S,9R,10S,11S,13R,14S,17S)-17-Acetyl-9-Fluoro-11-Hydroxy-10,13-Dimethyl-2,6,7,8,11,12,14,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthren-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; ensure containers are sealed under inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.