Description

3-Fluoro-4-Methoxybenzonitrile is a versatile fluorinated aromatic nitrile building block essential for advanced organic synthesis. Its molecular structure, featuring both electron-withdrawing and electron-donating substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This high-purity compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where its structure influences electronic properties and stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or unique surface properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reactions in cross-coupling, cyanation, and fluorination chemistry.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the fluorine and nitrile groups contribute to color fastness and molecular stability.

Basic Information

Product Name	3-Fluoro-4-Methoxybenzonitrile
CAS No.	331-62-4
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	4-Cyano-2-fluoroanisole; 2-Fluoro-4-cyanoanisole; 3-Fluoro-4-methoxybenzenecarbonitrile; 4-Methoxy-3-fluorobenzonitrile; 2-Fluoro-4-methoxybenzonitrile; Benzonitrile, 3-fluoro-4-methoxy-; 331-62-4; FCOC1=CC=C(OC)C(F)=C1
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methoxybenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.