Description

2-Amino-5-Cyanobenzotrifluoride is a high-value, multi-functional aromatic intermediate featuring both amino and cyano substituents on a trifluoromethylated benzene ring. This unique molecular structure makes it a critical building block for the synthesis of advanced, performance-oriented compounds. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Employed in the production of high-performance, light-fast dyes and organic pigments for specialized applications.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and electronic materials.

Basic Information

Product Name	2-Amino-5-Cyanobenzotrifluoride
CAS No.	327-74-2
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	2-Amino-5-cyanobenzotrifluoride; 2-Amino-α,α,α-trifluoro-p-tolunitrile; 5-Cyano-2-aminobenzotrifluoride; 2-Amino-α,α,α-trifluoro-4-cyanotoluene; 2-Amino-4-(trifluoromethyl)benzonitrile; 4-Cyano-2-aminobenzotrifluoride; Benzonitrile, 2-amino-α,α,α-trifluoro-; 2-Amino-α,α,α-trifluoro-4-cyanobenzene
EINECS	206-333-1

Quality Control

Every batch of 2-Amino-5-Cyanobenzotrifluoride is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the exacting standards required for fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.