Description

1-Ethoxy-2-Fluoro-4-Nitrobenzene is a specialized aromatic nitro compound featuring ethoxy and fluoro substituents. This unique structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for the development of complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for creating active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, pesticides, and fungicides, where the nitro and fluoro groups contribute to biological activity.
• Dye and Pigment Manufacturing: Serves as an intermediate for synthesizing specialized azo dyes and other colorants.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki-Miyaura couplings for constructing biaryl structures.
• Nucleophilic Aromatic Substitution: The presence of the fluoro and nitro groups makes it an excellent substrate for reactions with various nucleophiles.

Basic Information

Item	Details
Product Name	1-Ethoxy-2-Fluoro-4-Nitrobenzene
CAS No.	326-81-8
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	2-Fluoro-4-nitroanisole; 4-Nitro-2-fluoroanisole; 1-Ethoxy-2-fluoro-4-nitrobenzene; 2-Fluoro-1-methoxy-4-nitrobenzene; 2-Fluoro-4-nitro-1-methoxybenzene; 4-Nitro-2-fluoromethoxybenzene; 2-Fluoro-4-nitrophenyl methyl ether
EINECS	Contact for details

Quality Control

Our 1-Ethoxy-2-Fluoro-4-Nitrobenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, supporting your R&D and production requirements. Our quality systems are designed to meet the stringent demands of fine chemical and pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.