Description

1-Ethoxy-4-Fluoro-2-Nitrobenzene is a versatile aromatic nitro compound featuring both ethoxy and fluoro substituents. This chemical is a critical building block in advanced organic synthesis, valued for its unique electronic properties that facilitate selective chemical transformations. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic scaffolds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the nitro and fluoro groups impart specific biological activity.
• Organic Synthesis Building Block: Serves as a versatile starting material for palladium-catalyzed cross-coupling reactions, nucleophilic aromatic substitutions, and reduction reactions to yield aniline derivatives.
• Dye and Pigment Intermediate: Employed in the manufacture of specialized dyes and pigments, leveraging the nitro group as a chromophore precursor.
• Material Science Research: Used in academic and industrial R&D for creating novel organic electronic materials and liquid crystals.

Basic Information

Product Name	1-Ethoxy-4-Fluoro-2-Nitrobenzene
CAS No.	321-04-0
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	4-Fluoro-2-nitroanisole; 1-Ethoxy-4-fluoro-2-nitrobenzene; 2-Nitro-4-fluoroanisole; 4-Fluoro-2-nitro-1-ethoxybenzene; 2-Nitro-4-fluorophenetole; 1-Fluoro-4-ethoxy-2-nitrobenzene; Benzene, 1-ethoxy-4-fluoro-2-nitro-; p-Fluoro-o-nitroanisole
EINECS	Contact for details

Quality Control

Our 1-Ethoxy-4-Fluoro-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.