Description

4-Chloro-2-(Trifluoromethyl)Benzonitrile is a versatile aromatic nitrile building block distinguished by its chloro and trifluoromethyl substituents. This compound is valued for its role as a key intermediate in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs), where its unique halogenated structure imparts desirable biological activity and metabolic stability. It is primarily sought by research and development chemists and process engineers in the fine chemical, pharmaceutical, and agrochemical manufacturing sectors.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Pharmaceutical Building Block: Used in medicinal chemistry for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) targeting central nervous system and inflammatory diseases.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating advanced electronic chemicals and functional materials used in displays.
• Organic Synthesis & Research: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for generating compound libraries in drug discovery programs.
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and pigments where the cyano and halogen groups modify color and stability properties.

Basic Information

Item	Details
Product Name	4-Chloro-2-(Trifluoromethyl)Benzonitrile
CAS No.	320-41-2
Molecular Formula	C8H3ClF3N
Molecular Weight	205.56 g/mol
Synonyms	2-Trifluoromethyl-4-chlorobenzonitrile; 4-Chloro-α,α,α-trifluoro-o-tolunitrile; 4-Chloro-2-(trifluoromethyl)benzenecarbonitrile; 2-Cyano-5-chlorobenzotrifluoride; 4-Chloro-2-trifluoromethylbenzonitrile; 5-Chloro-2-(trifluoromethyl)benzonitrile; 320-41-2; Benzonitrile, 4-chloro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(Trifluoromethyl)Benzonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure consistency and compliance with customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.