Description

4-Nitro-3-(trifluoromethyl)benzonitrile is a high-purity, multi-functional aromatic intermediate featuring both a nitro and a trifluoromethyl group on a benzonitrile core. This unique structure makes it a valuable building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Intermediate for producing specialized dyes and pigments that require nitro and cyano functionalities for color and fastness properties.
• Polymer Modification: Used to introduce functional groups into polymer chains, enhancing thermal stability, chemical resistance, or surface properties.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic compounds and exploring new chemical reactions.

Basic Information

Product Name	4-Nitro-3-(trifluoromethyl)benzonitrile
CAS No.	320-36-5
Molecular Formula	C8H3F3N2O2
Molecular Weight	216.12 g/mol
Synonyms	3-(Trifluoromethyl)-4-nitrobenzonitrile; 4-Nitro-α,α,α-trifluoro-m-toluonitrile; 2-Nitro-5-cyanobenzotrifluoride; 5-Cyano-2-nitrobenzotrifluoride; 2-Nitro-α,α,α-trifluoro-m-toluonitrile; m-Toluonitrile, α,α,α-trifluoro-4-nitro-; 320-36-5; 4-Nitro-3-trifluoromethylbenzonitrile
EINECS	206-277-5

Quality Control

Our 4-Nitro-3-(trifluoromethyl)benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.