Description

1,3,5-Trifluoro-2-Nitrobenzene is a high-purity fluorinated aromatic nitro compound, serving as a critical building block in advanced organic synthesis. Its unique trifluoro-substituted nitrobenzene structure makes it an indispensable intermediate for creating complex molecules with tailored electronic and physical properties. This compound is primarily sought after by research and development laboratories, agrochemical manufacturers, and pharmaceutical companies for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or surface properties.
• Dye & Pigment Intermediate: Used in the synthesis of advanced colorants and fluorinated dyes for high-performance applications.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions, nucleophilic aromatic substitution, and other transformations to introduce fluorinated nitroaryl groups.

Basic Information

Product Name	1,3,5-Trifluoro-2-Nitrobenzene
CAS No.	315-14-0
Molecular Formula	C6H2F3NO2
Molecular Weight	177.08 g/mol
Synonyms	2-Nitro-1,3,5-trifluorobenzene; 1,3,5-Trifluoro-2-nitrobenzene; Benzene, 1,3,5-trifluoro-2-nitro-; NSC 404026; 315-14-0; α,α,α-Trifluoro-2,4,6-trinitrotoluene precursor; Trifluoronitrobenzene (isomer)
EINECS	206-247-9

Quality Control

Our 1,3,5-Trifluoro-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and traceable raw materials for GMP or research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.