Description

Dexamethasone Sodium Phosphate is a highly potent synthetic glucocorticoid corticosteroid, widely recognized for its anti-inflammatory and immunosuppressive properties. This water-soluble phosphate ester salt of dexamethasone is a critical active pharmaceutical ingredient (API) for formulating injectable and ophthalmic solutions. It is essential for pharmaceutical manufacturers, research institutions, and compounding pharmacies requiring a reliable, high-purity raw material for life-saving and therapeutic applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for treating severe inflammation, allergic reactions, and certain cancers.
• Ophthalmic Solutions: Key component in eye drops and ointments for managing inflammatory eye conditions such as uveitis and conjunctivitis.
• Veterinary Medicine: Used in anti-inflammatory and immunosuppressive treatments for companion animals and livestock.
• Research & Development: Vital reference standard and biochemical tool in pharmacological studies of steroid action and inflammation pathways.
• Hospital Compounding: Utilized in pharmacy compounding for preparing customized parenteral nutrition and specific patient-dose formulations.
• Topical Preparations: Incorporated into specialized creams and gels for targeted dermatological treatments under medical supervision.

Basic Information

Product Name	Dexamethasone Sodium Phosphate
CAS No.	312-93-6
Molecular Formula	C22H28FNa2O8P
Molecular Weight	516.39 g/mol
Synonyms	Dexamethasone 21-Phosphate Disodium Salt; Dexamethasone Phosphate Sodium; Dexamethasone Disodium Phosphate; 9α-Fluoro-16α-methylprednisolone 21-phosphate disodium salt; Oradexon; Decadron Phosphate; Hexadrol Phosphate; Dexpak Taperpak; Spersadex; Fortecortin
EINECS	206-222-5

Quality Control

Our Dexamethasone Sodium Phosphate is manufactured under strict quality management systems. We offer grades compliant with major pharmacopoeial standards, including USP and EP. Every batch undergoes comprehensive analytical testing, including assay, related substances, residual solvents, and microbiological examination, to ensure identity, purity, strength, and composition. A Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 8.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
pH (5% solution)	7.5 - 9.0
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.17 EU/mg (for injectable grade)
Sterility	Conforms (for sterile grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.