Description

3-(1-Aminoethyl)-4-Fluorobenzonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its benzonitrile core with aminoethyl and fluoro substituents. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modulation. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents, kinase inhibitors, and other specialized small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting neurological disorders and oncology.
• Chemical Research & Development: Serves as a versatile precursor for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides.
• Material Science: A potential monomer or additive in the development of specialty polymers and advanced functional materials.

Basic Information

Product Name	3-(1-Aminoethyl)-4-Fluorobenzonitrile Hydrochloride
CAS No.	2828439-96-7
Molecular Formula	C9H10FN2•HCl
Molecular Weight	200.65 (Free base) / 237.11 (HCl salt)
Synonyms	4-Fluoro-3-(1-aminoethyl)benzonitrile hydrochloride; 1-(4-Cyano-2-fluorophenyl)ethan-1-amine hydrochloride; 3-(1-Aminoethyl)-4-fluorobenzonitrile HCl; 3-(Aminoethyl)-4-fluorobenzonitrile hydrochloride; 4-Fluoro-3-(1-aminoethyl)benzonitrile HCl salt; α-Methyl-4-fluoro-m-cyanobenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(1-Aminoethyl)-4-Fluorobenzonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and current industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC & NMR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.