Description

Pregna-1,4,17(20)-Trien-21-Oic Acid, 9-Fluoro-11-Hydroxy-16-Methyl-3-Oxo-, (11β,16β,17E)- is a high-purity synthetic steroid derivative with a complex, modified pregnane backbone. This compound is of significant interest for its role as a critical pharmaceutical intermediate in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in advanced steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel corticosteroid analogs and other biologically active steroid molecules.
• Drug Discovery Research: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) and develop new anti-inflammatory or immunosuppressive agents.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in steroid analysis.
• Biochemical Research: Utilized in studies investigating steroid hormone receptor interactions and metabolic pathways.
• Process Chemistry Development: Acts as a starting material or intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Pregna-1,4,17(20)-Trien-21-Oic Acid, 9-Fluoro-11-Hydroxy-16-Methyl-3-Oxo-, (11β,16β,17E)-
CAS No.	2412496-00-3
Molecular Formula	C22H25FO4
Molecular Weight	372.43 g/mol
Synonyms	9-Fluoro-11β,16β-dihydroxy-16-methylpregna-1,4,17(20)-trien-3-one-21-oic acid; (11β,16β,17E)-9-Fluoro-11-hydroxy-16-methyl-3-oxopregna-1,4,17(20)-trien-21-oic acid; 9-Fluoro-11β-hydroxy-16β-methyl-3-oxo-1,4,17(20)-pregnatrien-21-oic acid; 16β-Methyl-9-fluoro-δ1,4,17(20)-pregnatriene-11β,21-diol-3-one-21-oic acid; Fluorinated Pregnatriene Derivative
EINECS	Contact for details

Quality Control

Our Pregna-1,4,17(20)-Trien-21-Oic Acid derivative is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.