Description

Pregna-1,4-Diene-3,20-Dione, 16,17-[Butylidenebis(Oxy)]-11-Hydroxy-21-(1-Oxobutoxy)-, (11β,16α)- is a high-purity, synthetic steroid derivative designed for advanced pharmaceutical research and development. This compound is critical for its role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of potent corticosteroid analogs. It is primarily required by pharmaceutical manufacturers and R&D laboratories focused on developing novel anti-inflammatory, immunosuppressive, and dermatological therapies. Our supply ensures consistent quality and reliable availability for critical global production and research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of advanced corticosteroid drugs.
• Active Pharmaceutical Ingredient (API) Research: Used in the development and formulation of new steroid-based medications targeting inflammation and immune response.
• Dermatological Preparations: A potential key component in the R&D of topical creams and ointments for treating severe skin conditions like psoriasis and eczema.
• Veterinary Pharmaceuticals: Employed in research for developing anti-inflammatory treatments for animals.
• Biochemical Research: Utilized as a reference standard or probe in studies investigating steroid receptor interactions and metabolic pathways.
• Process Development & Scale-Up: Supports process chemistry teams in optimizing synthetic routes for commercial-scale manufacturing.

Basic Information

Product Name	Pregna-1,4-Diene-3,20-Dione, 16,17-[Butylidenebis(Oxy)]-11-Hydroxy-21-(1-Oxobutoxy)-, (11β,16α)-
CAS No.	2408495-96-3
Molecular Formula	C29H38O7
Molecular Weight	498.61 g/mol
Synonyms	16α,17α-Butylidenebis(oxy)-11β-hydroxy-21-butyryloxypregna-1,4-diene-3,20-dione; 11β,21-Dihydroxy-16α,17α-butylidenedioxypregna-1,4-diene-3,20-dione 21-butyrate; Corticosteroid intermediate 2408495-96-3; Butylidenebis(oxy) Pregna Diene Dione Derivative; (11β,16α)-16,17-[Butylidenebis(oxy)]-11-hydroxy-21-(1-oxobutoxy)pregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Every batch of our Pregna-1,4-Diene-3,20-Dione derivative is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles are available for each lot. Our quality commitment aligns with cGMP principles where applicable, supporting regulatory filings and ensuring supply chain integrity for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.