Description

2,2,2-Trifluoroacetic Acid is a highly versatile and potent fluorinated organic acid. Its strong acidity and excellent solvent properties make it a critical reagent and solvent in advanced chemical synthesis and purification processes. This compound is essential for industries requiring high-performance fluorination chemistry and specialized organic transformations, including pharmaceutical development, agrochemical manufacturing, and materials science.

Application

• Pharmaceutical Synthesis: As a key reagent and solvent in the production of active pharmaceutical ingredients (APIs), particularly for peptide synthesis and as a mobile phase component in HPLC.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, pesticides, and plant growth regulators that incorporate fluorine for enhanced efficacy.
• Organic Synthesis & Catalysis: Serves as a strong acid catalyst and a protecting group remover (e.g., for t-butyl esters) in complex organic reactions.
• Polymer & Materials Science: Employed in the production of fluoropolymers and specialty materials where its properties aid in polymerization and modification processes.
• Analytical Chemistry: Utilized as a volatile ion-pairing agent and solvent in mass spectrometry and chromatographic applications for improved separation and detection.
• Chemical Intermediate: Acts as a crucial building block for synthesizing other fluorinated compounds, including pharmaceuticals, liquid crystals, and electronic chemicals.

Basic Information

Product Name	2,2,2-Trifluoroacetic Acid
CAS No.	2387602-00-6
Molecular Formula	C2HF3O2
Molecular Weight	114.02 g/mol
Synonyms	Trifluoroacetic Acid; TFA; Perfluoroacetic Acid; 2,2,2-Trifluoroethanoic Acid; Trifluoroethanoic Acid; CF3COOH; Trifluoracetic Acid; Kyselina trifluoroctova
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoroacetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality documentation, including Certificates of Analysis (COA) that detail purity, impurity profiles, and physical properties. Our quality protocols are designed to meet the stringent requirements of pharmaceutical (GMP), agrochemical, and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile and strong acid/organic solvent nature, ensure containers are kept upright and sealed when not in use to minimize fume release and moisture absorption.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.5%
Water Content (KF)	≤ 0.1%
Residue on Evaporation	≤ 0.01%
Chloride (Cl)	≤ 10 ppm
Sulfate (SO4)	≤ 10 ppm
Heavy Metals (as Pb)	≤ 5 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.