Description

Benzonitrile, 2-Fluoro-5-[(E)-(3-Oxo-1(3H)-Isobenzofuranylidene)Methyl]- is a specialized organic compound featuring a benzonitrile core fused with a phthalide-derived fluorinated chromophore. This unique molecular architecture makes it a high-value intermediate for advanced material synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics sectors for constructing complex molecules with specific optical or electronic properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific biological receptors.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or emissive layer dopants due to its conjugated system and fluorine substitution.
• Dye & Pigment Synthesis: Acts as a core structure for creating advanced fluorophores and functional dyes with tailored absorption/emission profiles.
• Liquid Crystal Materials: Potential intermediate for synthesizing fluorinated liquid crystal compounds used in display technologies.
• Academic & Contract Research: Employed in universities and CROs for methodological studies in organic synthesis and catalysis.

Basic Information

Product Name	Benzonitrile, 2-Fluoro-5-[(E)-(3-Oxo-1(3H)-Isobenzofuranylidene)Methyl]-
CAS No.	2377912-28-0
Molecular Formula	C₁₆H₈FNO₂
Molecular Weight	265.24 g/mol
Synonyms	2-Fluoro-5-[(E)-(3-oxo-1,3-dihydro-2-benzofuran-1-ylidene)methyl]benzonitrile; (E)-2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile; 1-(4-Cyano-3-fluorobenzylidene)isobenzofuran-3(1H)-one; 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]benzonitrile; Fluorinated Phthalide Benzonitrile Derivative
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 2-Fluoro-5-[(E)-(3-Oxo-1(3H)-Isobenzofuranylidene)Methyl]- adheres to a stringent quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting cGMP requirements for advanced intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.