Description

2-Iodo-3,3,3-Trifluoropropan-1-Ol is a specialized fluorinated and iodinated organic building block of significant interest in advanced synthetic chemistry. This compound matters for its unique molecular architecture, which combines a reactive iodo group with a trifluoromethyl moiety, enabling precise structural modifications in complex molecules. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the trifluoromethyl group into bioactive molecules, enhancing their metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides where fluorine substitution is critical for activity.
• Material Science Precursor: Serves as a building block for synthesizing fluorinated polymers and liquid crystals with unique properties.
• Cross-Coupling Reactions: The iodine atom makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Radical Chemistry: Acts as a source of trifluoromethyl and iodomethyl radicals in radical addition and cyclization reactions.
• Labeling and Tracer Studies: Potential use in the synthesis of compounds containing radioactive iodine-125 for diagnostic and research applications.

Basic Information

Product Name	2-Iodo-3,3,3-Trifluoropropan-1-Ol
CAS No.	2244087-13-4
Molecular Formula	C3H4F3IO
Molecular Weight	239.96 g/mol
Synonyms	2-Iodo-3,3,3-trifluoropropan-1-ol; 3,3,3-Trifluoro-2-iodopropan-1-ol; 2-Iodo-1,1,1-trifluoropropan-3-ol; 1,1,1-Trifluoro-3-iodo-2-propanol; 3-Iodo-1,1,1-trifluoropropan-2-ol; TFIP-I; Iodo-trifluoropropanol
EINECS	Contact for details

Quality Control

Our 2-Iodo-3,3,3-Trifluoropropan-1-Ol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development purposes. Each lot is analyzed using advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to the presence of iodine and the light-sensitive nature, prolonged exposure to light or heat should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.