Description

Arv-471 CAS NO 2229711-68-4 is a high-purity, small molecule pharmaceutical compound of significant interest in advanced therapeutic research. Its value lies in its targeted mechanism of action, making it a critical component for developing next-generation treatments. This product is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in oncology and related life science research.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key active pharmaceutical ingredient (API) or intermediate in preclinical and clinical-stage drug discovery programs.
• Oncology Drug Discovery: Utilized in the synthesis and study of novel targeted cancer therapies, particularly in hormone receptor-related pathways.
• Biochemical Assay Development: Acts as a reference standard or probe compound in high-throughput screening (HTS) and mechanism-of-action studies.
• Academic & Institutional Research: Used by universities and research institutes for fundamental biological studies and publications.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for potential commercial manufacturing.

Basic Information

Product Name	Arv-471
CAS No.	2229711-68-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ARV-471; Vepdegestrant; PF-07850327; (3S)-3-[4-[(2S)-2-[2-(2,6-Dichloro-3,5-dimethoxyphenyl)acetyl]-1,2,3,4-tetrahydroisoquinoline-6-carbonyl]piperazin-1-yl]piperidine-2,6-dione; PROTAC ER Degrader ARV-471
EINECS	Contact for details

Quality Control

Our Arv-471 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.