Description

Estrogen Receptor Antagonist 2 is a potent and selective small-molecule inhibitor designed for targeted research applications. This compound is critical for advancing studies in endocrinology and oncology, providing researchers with a precise tool to modulate estrogen receptor signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for hormone-dependent conditions.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery and preclinical development of novel anti-cancer and endocrine therapies.
• Biochemical Assay Development: Used as a selective ligand in competitive binding assays, reporter gene assays, and other in vitro screening platforms to study estrogen receptor (ER) alpha and beta activity.
• Mechanism of Action (MoA) Studies: Enables detailed investigation into the downstream effects of estrogen receptor antagonism on cell proliferation, apoptosis, and gene expression in relevant cell lines.
• Academic & Clinical Research: Supports fundamental research into hormone-responsive diseases, including breast cancer, ovarian cancer, and endometriosis, facilitating the exploration of new treatment paradigms.
• Drug Combination Studies: Employed in synergy studies to evaluate the efficacy of combination therapies involving hormone blockade and other chemotherapeutic or targeted agents.

Basic Information

Product Name	Estrogen Receptor Antagonist 2
CAS No.	2222844-89-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ER Antagonist 2; Selective Estrogen Receptor Downregulator (SERD) candidate; Estrogen Receptor Modulator 2; ER-alpha/beta inhibitor; Research Compound 2222844-89-3; Non-steroidal Anti-estrogen; Endocrine Disruptor Research Chemical
EINECS	Contact for details

Quality Control

Every batch of Estrogen Receptor Antagonist 2 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and documentation, including detailed Certificates of Analysis (COA) with supporting chromatographic data (HPLC, LC-MS). Our quality commitment aligns with the standards expected for pharmaceutical research materials, ensuring reliable and reproducible results for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.