Description

(5-(2-Fluorophenyl)-1-(Pyridin-3-Ylsulfonyl)-1H-Pyrrol-3-Yl) Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrole-sulfonamide scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The sulfonamide-pyrrole structure makes it a candidate for designing enzyme inhibitors.
• Kinase Inhibitor Synthesis: Potential building block for creating novel kinase-targeted therapeutic compounds.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of client-specific novel chemical entities (NCEs).

Basic Information

Product Name	(5-(2-Fluorophenyl)-1-(Pyridin-3-Ylsulfonyl)-1H-Pyrrol-3-Yl) Methanol
CAS No.	2169271-28-5
Molecular Formula	C₁₆H₁₃FN₂O₃S
Molecular Weight	332.35 g/mol
Synonyms	1H-Pyrrole-3-methanol, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)-; 5-(2-Fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-ylmethanol; 3-Pyridinesulfonamide, N-[5-(2-fluorophenyl)-3-(hydroxymethyl)-1H-pyrrol-1-yl]-; (5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanol; Fluorophenyl Pyridinylsulfonyl Pyrrole Methanol
EINECS	Contact for details

Quality Control

Our production of (5-(2-Fluorophenyl)-1-(Pyridin-3-Ylsulfonyl)-1H-Pyrrol-3-Yl) Methanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are manufactured and controlled under a quality system compliant with cGMP principles for advanced intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.