Description

3-Fluoro-5-Methoxy-2-Nitro Benzonitrile is a high-purity, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine and nitrile functionalities.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals due to its aromatic core and polar substituents.
• Organic Synthesis: A versatile reagent for palladium-catalyzed cross-coupling reactions and nucleophilic aromatic substitution (SNAr) chemistry.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-Fluoro-5-Methoxy-2-Nitro Benzonitrile
CAS No.	2167773-78-4
Molecular Formula	C8H5FN2O3
Molecular Weight	196.14 g/mol
Synonyms	2-Nitro-3-fluoro-5-methoxybenzonitrile; 3-Fluoro-5-methoxy-2-nitrobenzonitrile; Benzonitrile, 3-fluoro-5-methoxy-2-nitro-; 2167773-78-4; 3-Fluoro-5-methoxy-2-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a cGMP-compliant quality management system to ensure traceability and batch-to-batch consistency for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.