Description

Bis(Trifluoroacetic Acid) is a specialized, high-potency fluorinated organic acid derivative. This compound is valued for its strong acidity and unique reactivity profile, making it a critical reagent in advanced synthetic chemistry and material science. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring controlled trifluoroacetylation or as a precursor for complex fluorinated molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the trifluoromethyl group into active pharmaceutical ingredients (APIs), enhancing metabolic stability and lipophilicity.
• Agrochemical Production: Used in the synthesis of advanced herbicides and pesticides where fluorine atoms improve efficacy and environmental profile.
• Polymer & Material Science: Serves as a monomer or modifier in the development of fluorinated polymers with exceptional chemical and thermal resistance.
• Catalyst & Ligand Preparation: Employed in the synthesis of sophisticated organometallic catalysts and ligands for asymmetric synthesis.
• Analytical Chemistry: Acts as a derivatization agent or a mobile phase additive in chromatographic separations, particularly HPLC and LC-MS.
• Organic Synthesis Reagent: Utilized for esterification, amidation, and other acyl transfer reactions under mild conditions.

Basic Information

Item	Detail
Product Name	Bis(Trifluoroacetic Acid)
CAS No.	2102412-76-8
Molecular Formula	C4HF6O4 (Contact for details)
Molecular Weight	Contact for details
Synonyms	Bis(TFA); Di(trifluoroacetic) acid; Perfluorosuccinic acid derivative; Hexafluorosuccinic acid precursor; Trifluoroacetic anhydride homologue; 1,1,1,4,4,4-Hexafluoro-2,3-dioxobutane; TFAA dimer; Fluorinated dicarboxylic acid reagent
EINECS	Contact for details

Quality Control

Our Bis(Trifluoroacetic Acid) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by titration, identification by FT-IR, and impurity profiling by GC/HPLC, to ensure it meets the high-purity standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; containers must be kept tightly sealed and separated from bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (Titration)	≥ 95.0%
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.