Description

4-(1,1-Difluoro-2-Hydroxyethyl)Benzonitrile is a high-purity fluorinated benzonitrile derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both a nitrile and a difluorinated hydroxyethyl group, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Fluorinated Polymer Research: Employed as a monomer or modifier in the research and development of specialty polymers with unique surface and thermal properties.
• Chemical Biology & Proteomics: Acts as a versatile probe or linker in the development of chemical tools for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(1,1-Difluoro-2-Hydroxyethyl)Benzonitrile
CAS No.	2082663-46-3
Molecular Formula	C9H7F2NO
Molecular Weight	183.15 g/mol
Synonyms	4-(1,1-Difluoro-2-hydroxyethyl)benzonitrile; 2-(4-Cyanophenyl)-1,1-difluoroethanol; 1-(4-Cyanophenyl)-2,2-difluoroethanol; Benzonitrile, 4-(1,1-difluoro-2-hydroxyethyl)-; α,α-Difluoro-4-cyanophenethyl alcohol; 4-(α,α-Difluoro-β-hydroxyethyl)benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-(1,1-Difluoro-2-Hydroxyethyl)Benzonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.