Description

Trifluoromethyl 4-Fluorobenzenesulfonate is a high-purity, specialty organosulfur fluorination reagent. This compound is valued for its role as a versatile synthetic intermediate, enabling the efficient introduction of the trifluoromethylsulfonate (triflate) group into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine moiety enhances biological activity and stability.
• Material Science: Serves as a precursor in the creation of specialty polymers and liquid crystals with unique electronic or surface properties.
• Cross-Coupling Reactions: An effective electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing biaryl systems.
• Fluorination Reagent: Acts as a source of the trifluoromethanesulfonyl (triflyl) group in nucleophilic substitution reactions.
• Chemical Research: Employed in academic and industrial R&D labs for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	Trifluoromethyl 4-Fluorobenzenesulfonate
CAS No.	2070902-77-9
Molecular Formula	C7H4F4O3S
Molecular Weight	244.17 g/mol
Synonyms	4-Fluorophenyl trifluoromethanesulfonate; p-Fluorophenyl triflate; 1-Fluoro-4-(trifluoromethanesulfonyloxy)benzene; 4-Fluorophenyl triflate; Trifluoromethanesulfonic acid 4-fluorophenyl ester; 4-Fluorobenzenesulfonyl trifluoromethane; (4-Fluorophenyl) trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our Trifluoromethyl 4-Fluorobenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.