Description

Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Fluoro-, (2S)- (9Ci) is a high-purity, chiral fluorinated amino acid derivative, specifically engineered as a critical building block for advanced pharmaceutical synthesis. This compound matters for its role in introducing fluorine atoms and specific stereochemistry into complex molecules, a key strategy for modulating the metabolic stability, bioavailability, and potency of new drug candidates. Pharmaceutical R&D and process chemistry teams need this high-quality intermediate to develop novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas like oncology and neurology.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Peptidomimetic Synthesis: Used to incorporate fluorinated amino acid residues into peptide analogs to enhance metabolic stability and binding affinity.
• Protease Inhibitor Development: Serves as a building block for inhibitors targeting specific enzymes involved in disease pathways.
• Labeled Compound Precursor: Acts as a starting material for synthesizing isotopically labeled compounds for pharmacokinetic and metabolic studies.
• Agrochemical Research: Employed in the discovery of new fluorinated compounds with potential herbicidal or pesticidal activity.
• Material Science: Investigated for the synthesis of specialized fluorinated polymers and advanced organic materials.

Basic Information

Product Name	Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Fluoro-, (2S)- (9Ci)
CAS No.	294858-41-6
Molecular Formula	C9H16FNO4
Molecular Weight	221.23 g/mol
Synonyms	(2S)-2-Fluoro-3-[(tert-butoxycarbonyl)amino]propanoic acid; Boc-Fluoro-DL-alanine (related); N-Boc-3-amino-2-fluoropropionic acid; 3-[(tert-Butoxycarbonyl)amino]-2-fluoropropanoic acid; 2-Fluoro-3-[(tert-butoxycarbonyl)amino]propionic acid; (S)-2-Fluoro-3-((tert-butoxycarbonyl)amino)propanoic acid; N-Boc-2-fluoro-β-alanine derivative; Fluorinated Boc-protected amino acid
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Fluoro-, (2S)- (9Ci) is manufactured under strict quality systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.