Description

7-Oxabicyclo[2.2.1]Hept-2-Ene,5,5,6-Trifluoro-1-Methyl-,(1R,4S,6R)-Rel-(9Ci) is a high-purity, stereochemically defined fluorinated oxanorbornene derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique bicyclic structure and fluorine substitution pattern make it a valuable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring fluorinated motifs.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the oxabicyclic core and fluorine atoms enhance biological activity and environmental stability.
• Material Science: Acts as a monomer or precursor for synthesizing specialized polymers and advanced materials with unique optical or electronic properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development and screening of new asymmetric catalytic systems.
• Fluorine Chemistry Research: A valuable compound for studying structure-activity relationships (SAR) and the effects of fluorine substitution on molecular conformation and reactivity.
• Fine Chemical Synthesis: Serves as a versatile intermediate for the custom synthesis of complex, high-value fine chemicals for various industrial applications.

Basic Information

Product Name	7-Oxabicyclo[2.2.1]Hept-2-Ene,5,5,6-Trifluoro-1-Methyl-,(1R,4S,6R)-Rel-(9Ci)
CAS No.	292820-82-7
Molecular Formula	C7H7F3O
Molecular Weight	164.13 g/mol
Synonyms	(1R,4S,6R)-5,5,6-Trifluoro-1-methyl-7-oxabicyclo[2.2.1]hept-2-ene; rel-(1R,4S,6R)-5,5,6-Trifluoro-1-methyl-7-oxabicyclo[2.2.1]hept-2-ene; 5,5,6-Trifluoro-1-methyl-7-oxabicyclo[2.2.1]hept-2-ene (rel-(1R,4S,6R)-); Fluorinated Oxanorbornene Derivative; Trifluoromethyl Oxanorbornene; Chiral Fluorinated Bicyclic Ether
EINECS	Contact for details

Quality Control

Every batch of 7-Oxabicyclo[2.2.1]Hept-2-Ene,5,5,6-Trifluoro-1-Methyl-,(1R,4S,6R)-Rel-(9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, typically including chiral HPLC analysis to confirm enantiomeric/excess. Certificates of Analysis (COA) detailing specific batch results are available upon request, supporting compliance with research and cGMP guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.