Description

Cyclohexanecarboxylic acid, 2-[(propylamino)carbonyl]-, (1R,2R)-, fluoride (9CI) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in the precise (1R,2R)- configuration and the reactive acyl fluoride moiety, which enables efficient coupling reactions under mild conditions. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for constructing complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its stereochemistry can influence biological activity and selectivity.
• Peptide Mimetics & Conjugation: The acyl fluoride group facilitates efficient amide bond formation, making it valuable for creating peptide analogs or conjugating molecules to carriers.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new asymmetric catalytic processes.
• Material Science Precursor: Potential use in synthesizing specialized monomers for polymers with tailored properties.
• Chemical Biology Probes: Employed to create activity-based probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Cyclohexanecarboxylic acid, 2-[(propylamino)carbonyl]-, (1R,2R)-, fluoride (9CI)
CAS No.	288314-21-6
Molecular Formula	C11H18FNO2
Molecular Weight	215.27 g/mol
Synonyms	(1R,2R)-2-[(Propylcarbamoyl)]cyclohexanecarbonyl Fluoride; (1R,2R)-Cyclohexanecarbonyl Fluoride, 2-[(Propylamino)Carbonyl]-; (1R,2R)-N-Propyl-2-(fluorocarbonyl)cyclohexanecarboxamide; trans-2-(Propylcarbamoyl)cyclohexanecarbonyl Fluoride; 288314-21-6; (1R,2R)-2-(Propylcarbamoyl)cyclohexane-1-carbonyl fluoride
EINECS	Contact for details

Quality Control

Every batch of our Cyclohexanecarboxylic acid, 2-[(propylamino)carbonyl]-, (1R,2R)-, fluoride is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and enantiomeric excess meet exacting standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent derivative and high volatility, ensure containers are sealed under an inert atmosphere if specified and kept away from heat, sparks, and open flames. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.