Description

Benzonitrile, 5-Acetyl-2-Fluoro- (9Ci) CAS NO 288309-07-9 is a high-purity fluorinated aromatic nitrile derivative, serving as a critical advanced intermediate in modern organic synthesis. Its molecular structure, featuring both acetyl and fluorine substituents on the benzonitrile core, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its polar nitrile group and aromatic system.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	Benzonitrile, 5-Acetyl-2-Fluoro- (9Ci)
CAS No.	288309-07-9
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	5-Acetyl-2-fluorobenzonitrile; 2-Fluoro-5-acetylbenzonitrile; 1-(3-Cyano-4-fluorophenyl)ethanone; 3-Cyano-4-fluoroacetophenone; 288309-07-9; 5-Acetyl-2-fluorobenzonitrile (9CI); Ethanone, 1-(3-cyano-4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our Benzonitrile, 5-Acetyl-2-Fluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.