Description

Benzonitrile, 4-(Aminooxy)-2-Fluoro- (9Ci) CAS NO 269056-55-5 is a high-purity, fluorinated aromatic nitrile derivative featuring a reactive aminooxy functional group. This compound is a critical pharmaceutical intermediate and bioconjugation reagent, enabling the synthesis of complex molecules through oxime bond formation. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing targeted drug candidates and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of oxime-linked active pharmaceutical ingredients (APIs), particularly in oncology and targeted therapies.
• Bioconjugation Reagent: Used for site-specific labeling and modification of proteins, antibodies, and peptides for diagnostics and biotherapeutics.
• Agrochemical Synthesis: Intermediate in the production of novel herbicides and fungicides with enhanced activity and selectivity.
• Polymer Functionalization: Imparts reactive sites onto polymer backbones for creating advanced materials with tailored surface properties.
• Chemical Biology Probes: Enables the development of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Linker Chemistry: Serves as a versatile linker for solid-phase synthesis and the creation of drug-delivery conjugates.

Basic Information

Product Name	Benzonitrile, 4-(Aminooxy)-2-Fluoro- (9Ci)
CAS No.	269056-55-5
Molecular Formula	C7H5FN2O
Molecular Weight	152.13 g/mol
Synonyms	2-Fluoro-4-(aminooxy)benzonitrile; 4-(Aminooxy)-2-fluorobenzonitrile; 2-Fluoro-4-hydroxyaminobenzonitrile; 4-(Hydroxyamino)-2-fluorobenzonitrile; 2-Fluoro-4-(hydroxyamino)benzonitrile; 4-Aminooxy-2-fluorobenzonitrile; (4-Cyano-3-fluorophenyl)hydroxylamine; 269056-55-5
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-(Aminooxy)-2-Fluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO compliant workflows for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.