Description

2-Chloro-6-Fluorobenzoylacetonitrile is a versatile and high-value fluorinated aromatic intermediate. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research institutions and manufacturers developing active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty organic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine and chlorine substituents for enhanced biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new organic reactions and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-6-Fluorobenzoylacetonitrile
CAS No.	267881-03-8
Molecular Formula	C9H5ClFNO
Molecular Weight	197.59 g/mol
Synonyms	2-Chloro-6-fluorobenzoylacetonitrile; 3-(2-Chloro-6-fluorophenyl)-3-oxopropanenitrile; 2-Chloro-6-fluoro-ω-cyanacetophenone; 2-Chloro-6-fluorobenzoyl methyl cyanide; (2-Chloro-6-fluorophenyl)(cyano)methanone; Acetonitrile, (2-chloro-6-fluorobenzoyl)-; 267881-03-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluorobenzoylacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.