Description

Benzenepropanenitrile, 2,4-Difluoro-5-Nitro-B-Oxo- is a high-value, multi-functional nitrile derivative featuring a strategically substituted aromatic ring. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic organic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the difluoro and nitro groups contribute to enhanced bioactivity and selectivity.
• Ligand and Catalyst Development: Serves as a sophisticated precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds due to its electron-accepting nitro and nitrile functionalities.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Benzenepropanenitrile, 2,4-Difluoro-5-Nitro-B-Oxo-
CAS No.	267880-97-7
Molecular Formula	C9H4F2N2O2
Molecular Weight	210.14 g/mol
Synonyms	2,4-Difluoro-5-nitro-β-oxobenzene propanenitrile; 3-(2,4-Difluoro-5-nitrophenyl)-3-oxopropanenitrile; 2,4-Difluoro-5-nitrobenzoylacetonitrile; 2,4-Difluoro-5-nitro-ω-cyanacetophenone; (2,4-Difluoro-5-nitrophenyl)-3-oxopropanenitrile; 3-Oxo-3-(2,4-difluoro-5-nitrophenyl)propanenitrile; DNBPO Nitrile
EINECS	Contact for details

Quality Control

Our production of Benzenepropanenitrile, 2,4-Difluoro-5-Nitro-B-Oxo- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for identity confirmation and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.