Description

Benzenepropanenitrile, 4-Chloro-3-Fluoro-B-Oxo- is a high-value fluorinated aromatic nitrile building block, distinguished by its unique halogenated and oxo-functionalized structure. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced electronic materials due to its polarizable aromatic system and functional handles.
• Organic Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Utilized in exploratory chemistry for the discovery of new chemical entities and material properties.

Basic Information

Product Name	Benzenepropanenitrile, 4-Chloro-3-Fluoro-B-Oxo-
CAS No.	267880-80-8
Molecular Formula	C9H5ClFNO
Molecular Weight	197.59 g/mol
Synonyms	4-Chloro-3-fluorobenzoylacetonitrile; 3-(4-Chloro-3-fluorophenyl)-3-oxopropanenitrile; 4-Chloro-3-fluoro-β-oxobenzenepropanenitrile; (4-Chloro-3-fluorobenzoyl)acetonitrile; 1-(4-Chloro-3-fluorophenyl)-2-cyanoethan-1-one; 2-(4-Chloro-3-fluorobenzoyl)acetonitrile; 4-Chloro-3-fluoro-ω-oxobenzenepropanenitrile
EINECS	Contact for details

Quality Control

Our production of Benzenepropanenitrile, 4-Chloro-3-Fluoro-B-Oxo- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.