Description

2,2-Difluoro-2-Pyridin-2-Ylethanamine is a specialized fluorinated pyridine derivative, serving as a high-value building block in advanced organic synthesis. Its core value lies in the introduction of a difluoroethylamine moiety adjacent to a pyridine ring, enabling precise modulation of molecular properties such as lipophilicity, metabolic stability, and binding affinity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel nitrogen-containing ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials that require fluorinated aromatic components for specific performance characteristics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	2,2-Difluoro-2-Pyridin-2-Ylethanamine
CAS No.	267875-68-3
Molecular Formula	C7H8F2N2
Molecular Weight	158.15 g/mol
Synonyms	2-(2,2-Difluoroethyl)pyridine; 2-Pyridineethanamine, 2,2-difluoro-; 2,2-Difluoro-2-(2-pyridinyl)ethanamine; 2-(2,2-Difluoroethyl)pyridinamine; α,α-Difluoro-2-pyridineethanamine; 2-(Pyridin-2-yl)-2,2-difluoroethanamine; 2,2-Difluoro-2-(pyridin-2-yl)ethan-1-amine
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-Pyridin-2-Ylethanamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support development and commercial projects requiring material that meets stringent internal specifications or compendial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.