Description

Benzonitrile, 3-Acetyl-4-Fluoro- (9Ci) is a high-purity fluorinated aromatic nitrile building block, identified by CAS NO 267875-54-7. This compound is valued for its unique molecular structure, which combines an electron-withdrawing nitrile group with an acetyl substituent and a fluorine atom, making it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, where its aromatic and polar nitrile group contributes to desired material properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a substrate for introducing the acetyl-fluorobenzonitrile moiety into more complex structures.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in related chemical production.

Basic Information

Product Name	Benzonitrile, 3-Acetyl-4-Fluoro- (9Ci)
CAS No.	267875-54-7
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	3-Acetyl-4-fluorobenzonitrile; 4-Fluoro-3-acetylbenzonitrile; 1-(4-Fluoro-3-cyanophenyl)ethan-1-one; 3-Cyano-4-fluoroacetophenone; 4-Fluoro-3-cyanobenzophenone; 3-Acetyl-4-fluorophenyl cyanide; 4-Fluoro-3-acetylphenyl cyanide
EINECS	Contact for details

Quality Control

Our Benzonitrile, 3-Acetyl-4-Fluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.